Description |
Lamiide, an orally active iridoid compound, can be found in Bouchea fluminensis leaves. Lamiide exhibits anti-inflammatory and anti-lipoperoxidative activity[1].
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In Vitro |
Lamiide inhibits rat-brain phospholipid peroxidation, with an IC50 of 0.92 mM[1].
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In Vivo |
Lamiide (12.5-100 mg/kg; p.o. 30 min before Carrageenin injection) dose-dependently reduces Carrageenin-induced edema[1]. Animal Model: Female Wistar rats (8-weeks old, 150-200 g) were injected with Carrageenin in the subplantar aponeurosis of the right hind paw[1] Dosage: 12.5, 25, 50, 100 mg/kg Administration: P.o. 30 min before Carrageenin injection Result: Reduced Carrageenin-induced edema, with an ED50 of 62.3 mg/kg.
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Density | 1.7±0.1 g/cm3 |
Boiling Point | 667.2±55.0 °C at 760 mmHg |
Flash Point | 237.8±25.0 °C |
Exact Mass | 422.142426 |
PSA | 195.60000 |
LogP | -3.03 |
Vapour Pressure | 0.0±4.6 mmHg at 25°C |
Storage condition | ?20°C |