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(-)-Hydroxycitric acid lactone
| Product Name | (-)-Hydroxycitric acid lactone |
| Price: | Inquiry |
| Catalog No.: | CN06380 |
| CAS No.: | 27750-13-6 |
| Molecular Formula: | C6H6O7 |
| Molecular Weight: | 190.1 g/mol |
| Purity: | >=98% |
| Type of Compound: | Miscellaneous |
| Physical Desc.: | Powder |
| Source: | The resins of Garcinia hanburyi |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | (-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a popular weight loss food supplement. (-)-Hydroxycitric acid lactone is a potent inhibitor of ATP-citrate lyase. (-)-Hydroxycitric acid lactone catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA, limits the availability of acetyl-CoA units required for fatty acid synthesis[1][2]. |
| In Vivo | (-)-Hydroxycitric acid lactone (1000-3000mg/kg; fed for a period of 4 weeks) significantly decreases body weight at 2000 and 3000 mg/kg in chicken[2]. Animal Model: 1-day-old male broiler chickens[2] Dosage: 1000, 2000, 3000 mg/kg Administration: Fed for a period of 4 weeks Result: Body weight and average daily gain (ADG) in the 2000 mg/kg and 3000 mg/kg were significantly lower. |
| Density | 1.976 |
| Exact Mass | 190.01100 |
| PSA | 121.13000 |