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Mesaconitine
| Product Name | Mesaconitine |
| Price: | Inquiry |
| Catalog No.: | CN02207 |
| CAS No.: | 2752-64-9 |
| Molecular Formula: | C33H45NO11 |
| Molecular Weight: | 631.71 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | The roots of Aconitum carmichaeli Debx. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COCC12CN(C)C3C4(C2C(OC)C3C2(C3C4CC(C3OC(=O)c3ccccc3)(C(C2O)OC)O)OC(=O)C)C(CC1O)OC |
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| Description | Mesaconitine is the main active component of genus aconitum plants.IC50 value:Target: in vitro: In HUVECs, 30 microM mesaconitine increased the [Ca(2+)](i) level in the presence of extracellular CaCl(2) and NaCl, and the response was inhibited by KBR7943. Mesaconitine increased intracellular Na(+) concentration level in HUVECs. The [Ca(2+)](i) response by mesaconitine was inhibited by 100 microM D-tubocurarine [1]. Mesaconitine at 30 microM inhibited 3 microM phenylephrine-induced contraction in the endothelium-intact, but not endothelium-denuded, aortic rings [2]. MA promoted the alpha-MT-induced decrease in NE levels in hippocampus, medulla oblongata plus pons and spinal cord [3]. |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 695.0±55.0 °C at 760 mmHg |
| Flash Point | 374.1±31.5 °C |
| Exact Mass | 631.299255 |
| PSA | 153.45000 |
| LogP | 0.27 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |