Home
Products
Neocryptotanshinone II
| Product Name | Neocryptotanshinone II |
| Price: | Inquiry |
| Catalog No.: | CN08637 |
| CAS No.: | 27468-20-8 |
| Molecular Formula: | C19H22O3 |
| Molecular Weight: | 298.4 g/mol |
| Purity: | >=98% |
| Type of Compound: | Diterpenoids |
| Physical Desc.: | Powder |
| Source: | The roots of Salvia miltiorrhiza Bge. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
| Contact us | |
|---|---|
| First Name: | |
| Last Name: | |
| E-mail: | |
| Question: | |
| Description | Deoxyneocryptotanshinone, a natural tanshinone, is a high affinity BACE1 (Beta-secretase) inhibitor with an IC50 value of 11.53 μM. Deoxyneocryptotanshinone shows a promising dose-dependent inhibition of protein tyrosine phosphatase 1B (PTP1B) with an IC50 value of 133.5 μM. Deoxyneocryptotanshinone can be used for Alzheimer's disease research[1][2]. |
| Target | IC50: 11.53 μM (BACE1)[1] and 133.5 μM (PTP1B)[2] |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 468.0±45.0 °C at 760 mmHg |
| Flash Point | 251.0±25.2 °C |
| Exact Mass | 298.156891 |
| PSA | 54.37000 |
| LogP | 5.74 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |