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Bruceine A
| Product Name | Bruceine A |
| Price: | $146 / 10mg |
| Catalog No.: | CN08320 |
| CAS No.: | 25514-31-2 |
| Molecular Formula: | C26H34O11 |
| Molecular Weight: | 522.54 g/mol |
| Purity: | >=98% |
| Type of Compound: | Diterpenoids |
| Physical Desc.: | Powder |
| Source: | The fruits of Brucea javanica (L.) Merr. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COC(=O)[C@@]12OC[C@]34[C@H]2[C@@H](OC(=O)CC(C)C)C(=O)O[C@@H]4C[C@@H]2[C@]([C@H]3[C@H]([C@@H]1O)O)(C)CC(=O)C(=C2C)O |
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| Description | Bruceine A(NSC310616; Dihydrobrusatol) is a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.); are potential candidates for the treatment of canine babesiosis.IC50 value:Target: Bruceine A inhibited the in vitro growth of Babesia gibsoni in canine erythrocytes at lower concentration compared with the standard antibabesial drug diminazene aceturate and killed the parasites within 24 hr at a concentration of 25 nM. Oral administration of bruceine A at a dosage of 6.4 mg/kg/day for 5 days resulted in no clinical findings in a dog with normal ranges of hematological and biochemical values in the blood. Three dogs were infected with B. gibsoni and two of them were treated with bruceine A at a dosage of 6.4 mg/kg/day for 6 days from day 5 post-infection. |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 712.6±60.0 °C at 760 mmHg |
| Flash Point | 237.1±26.4 °C |
| Exact Mass | 522.210083 |
| PSA | 165.89000 |
| LogP | 1.80 |
| Vapour Pressure | 0.0±5.2 mmHg at 25°C |
| Storage condition | -20°C |