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Nardosinone
| Product Name | Nardosinone |
| Price: | $77 / 20mg |
| Catalog No.: | CN09376 |
| CAS No.: | 23720-80-1 |
| Molecular Formula: | C15H22O3 |
| Molecular Weight: | 250.33 g/mol |
| Purity: | >=98% |
| Type of Compound: | Sesquiterpenoids |
| Physical Desc.: | Powder |
| Source: | The roots of Nardostachys jatamansi DC. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | O=C1C[C@H]2OOC([C@H]2[C@@]2(C1=CCC[C@H]2C)C)(C)C |
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| Description | Nardosinone, isolated from Nardostachys chinensis, is the first enhancer of the neuritogenic action of dbcAMP and staurosporine. Nardosinone may become a useful pharmacological tool for studying the mechanism of action of not only nerve growth factor (NGF) but also both the neuritogenic substances[1]. |
| In Vitro | Nardosinone (0.1-100 microM) enhanced dibutyryl cyclic AMP (dbcAMP, 0.3 mM)- and staurosporine (10 nM)-induced neurite outgrowth from PC12D cells in a concentration-dependent manner. Nardosinone enhances a downstream step of MAP kinase in the MAP kinase-dependent signaling pathway[1]. |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 330.2±32.0 °C at 760 mmHg |
| Flash Point | 142.0±25.2 °C |
| Exact Mass | 250.156891 |
| PSA | 35.53000 |
| LogP | 3.04 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Storage condition | 2-8C |