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Sinensetin
| Product Name | Sinensetin |
| Price: | $103 / 20mg |
| Catalog No.: | CN05513 |
| CAS No.: | 2306-27-6 |
| Molecular Formula: | C20H20O7 |
| Molecular Weight: | 372.37 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Yellow powder |
| Source: | The fruits of Citrus aurantium L. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COc1ccc(cc1OC)c1cc(=O)c2c(o1)cc(c(c2OC)OC)OC |
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| Description | Sinensetin is a methylated flavone found in certain citrus fruits. pocess potent antiangiogenesis and anti-inflammatory, sinensetin enhances adipogenesis and lipolysis.In vitro: Sinensetin promots adipogenesis in 3T3-L1 preadipocytes growing in incomplete differentiation medium, sinensetin enhances adipogenesis and lipolysis by increasing cAMP levels. [1] Sinensetin shows anti-inflammatory activity by regulating the protein level of inhibitor κB-α (IκB-α). [2]In vivo: Sinensetin has the most potent antiangiogenesis activity and the lowest toxicity, inhibits angiogenesis by inducing cell cycle arrest in the G0/G1 phase in HUVEC culture and downregulating the mRNA expressions of angiogenesis genes flt1, kdrl, and hras in zebrafish. [3] |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 547.8±50.0 °C at 760 mmHg |
| Flash Point | 240.6±30.2 °C |
| Exact Mass | 372.120911 |
| PSA | 76.36000 |
| LogP | 3.08 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Storage condition | 2-8°C |