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Norwogonin 5,7,8-trimethyl ether
| Product Name | Norwogonin 5,7,8-trimethyl ether |
| Price: | $293 / 20mg |
| Catalog No.: | CN04469 |
| CAS No.: | 23050-38-6 |
| Molecular Formula: | C18H16O5 |
| Molecular Weight: | 312.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Powder |
| Source: | The roots of Scutellaria indica L. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COc1cc(OC)c2c(c1OC)oc(cc2=O)c1ccccc1 |
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| Description | 5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether), isolated from Andrographis echioides, inhibits NO with an IC50 of 39.1 μM. 5,7,8-Trimethoxyflavone has anti-inflammatory activity[1]. |
| In Vitro | 5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether; 8, 16, 32, 64 μM; for 24 hours) decreases NO production in a dose-dependent manner in RAW 264.7 macrophages. 5,7,8-Trimethoxyflavone does not change lipopolysaccharide (LPS)-induced (100 ng/mL) cell viability[1]. |
| Density | 1.242±0.06 g/cm3 at 760 mmHg |
| Boiling Point | 507.4±50.0 °C at 760 mmHg |
| Storage condition | 2-8°C |