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Isoescin IB
| Product Name | Isoescin IB |
| Price: | $234 / 5mg |
| Catalog No.: | CN07518 |
| CAS No.: | 219944-46-4 |
| Molecular Formula: | C55H86O24 |
| Molecular Weight: | 1131.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Triterpenoids |
| Physical Desc.: | Powder |
| Source: | The herbs of Aesculus hippocastanum L. |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: |
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| Description | Isoescin IB, isolated from horse chestnut tree seeds, is an isomer of Escin IB. Isoescin IB and Escin IB are the chief active ingredients in escin[1]. |
| In Vitro | β-Escin (mainly consisting of escin Ia and escin Ib) is the major active ingredient in horse chestnut seeds extracts. β-escin can inhibit proliferation and/or induce apoptosis in various types of cancer cells including A549 cell, HT-29 cell, HCC cell, OVCAR3 cell and H-Ras 5RP7 cell. β-escin may be useful as a chemopreventive agent, especially for tumors associated with an inflammatory response[1]. As the minor component of escin, α-escin (mainly consisting of isoescin Ia and isoescin Ib) exhibits lower bioactivity[1]. |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 1148.1±65.0 °C at 760 mmHg |
| Flash Point | 314.2±27.8 °C |
| Exact Mass | 1130.550903 |
| LogP | 2.17 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |