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Product Name | Protocatechuic acid methyl ester |
Price: | Inquiry |
Catalog No.: | CN03845 |
CAS No.: | 2150-43-8 |
Molecular Formula: | C8H8O4 |
Molecular Weight: | 168.2 g/mol |
Purity: | >=98% |
Type of Compound: | Phenols |
Physical Desc.: | Powder |
Source: | The stems of Bauhinia manca |
Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
SMILES: | COC(=O)c1ccc(c(c1)O)O |
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Description | Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester;Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect[1]. |
In Vitro | Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester;Methyl protocatechuate) alleviates the toxic effects of F- via modulating its bioavailability, intracellular calcium level, mitochondrial membrane integrity and redox signaling in A549 cells[1]. |
In Vivo | Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester;Methyl protocatechuate) (25 or 50 mg/kg bw/day) prevents the cellular F- accumulation and oxidative stress. It prevents the inflammatory and associated fibrosis progression by restoring the expression of RAGE and Nrf2[2]. |
Density | 1.4±0.1 g/cm3 |
Boiling Point | 351.5±22.0 °C at 760 mmHg |
Flash Point | 148.5±15.8 °C |
Exact Mass | 168.042252 |
PSA | 66.76000 |
LogP | 1.69 |
Vapour Pressure | 0.0±0.8 mmHg at 25°C |