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1,11b-Dihydro-11b-hydroxymedicarpin
| Product Name | 1,11b-Dihydro-11b-hydroxymedicarpin |
| Price: | Inquiry |
| Catalog No.: | CN04937 |
| CAS No.: | 210537-04-5 |
| Molecular Formula: | C16H16O5 |
| Molecular Weight: | 288.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Powder |
| Source: | The herbs of Derris robusta |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | 1,11b-Dihydro-11b-hydroxymedicarpin (11b-Hydroxy-11b,1-dihydromedicarpin) is a pterocarpan from Ononis viscosa subsp. breviflora is a Medicarpin derivative[1]. Medicarpin, a natural pterocarpan, heals cortical bone defect by activation of Notch and Wnt canonical signaling pathways[2]. Medicarpin prevents arthritis in post-menopausal conditions by arresting the expansion of TH17 cells and pro-inflammatory cytokines. Medicarpin down-regulates pro-inflammatory cytokines like TNF-α, IL-6 and IL-17A, while up-regulates anti-inflammatory cytokine IL-10 in arthritis (CIA) model of mice[3]. |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 490.0±45.0 °C at 760 mmHg |
| Flash Point | 185.8±22.2 °C |
| Exact Mass | 288.099762 |
| PSA | 64.99000 |
| LogP | 1.36 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |