Description |
Luteolin-7-rutinoside has both anti-arthritic and antifungal activities, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.
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In Vitro |
At a dose of 10 μg Luteolin-7-rutinoside (lonicerin)/mL, there is an approximately 47% decrease of the proliferation as compared to proliferation of Luteolin-7-rutinoside treated (control) T cells (p<0.05). Luteolin-7-rutinoside at 40 μg/mL dose give almost the same rate of T cell proliferation as does 20 μg/mL dose of Luteolin-7-rutinoside. The suppressive activity is dose dependent. Luteolin-7-rutinoside treatment swifts Th1-Th2 balance away from Th1-toward Th2-type responses. Luteolin-7-rutinoside inhibits nitric oxide (NO) production from macrophages[1].
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Density | 1.8±0.1 g/cm3 |
Boiling Point | 954.0±65.0 °C at 760 mmHg |
Flash Point | 316.9±27.8 °C |
Exact Mass | 594.158447 |
LogP | 1.35 |
Vapour Pressure | 0.0±0.3 mmHg at 25°C |