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Tetrahydromagnolol
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Product Name Tetrahydromagnolol
Price: $131 / 10mg
Catalog No.: CN02684
CAS No.: 20601-85-8
Molecular Formula: C18H22O2
Molecular Weight: 270.4 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Source: The barks of Magnolia officinalis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
SMILES: CCCc1ccc(c(c1)c1cc(CCC)ccc1O)O
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Description Tetrahydromagnolol (Magnolignan), a main metabolite of Magnolol, is a potent and selective cannabinoid CB2 receptor agonist with an EC50 of 170 nM and a Ki of 416 nM. Tetrahydromagnolol possesses 20-fold more selective for CB2 receptor than CB1 receptor. Tetrahydromagnolol is also a weak GPR55 receptor antagonist[1].
Target CB2:170 nM (EC50) CB2:416 nM (Ki) CB1:9010 nM (EC50) CB1:2260 nM (Ki) GPR55 receptor
Density1.1±0.1 g/cm3
Boiling Point400.5±40.0 °C at 760 mmHg
Flash Point182.2±21.9 °C
Exact Mass270.161987
PSA40.46000
LogP4.95
Vapour Pressure0.0±1.0 mmHg at 25°C