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Furanodiene
| Product Name | Furanodiene |
| Price: | Inquiry |
| Catalog No.: | CN09047 |
| CAS No.: | 19912-61-9 |
| Molecular Formula: | C15H20O |
| Molecular Weight: | 216.15 g/mol |
| Purity: | >=98% |
| Type of Compound: | Sesquiterpenoids |
| Physical Desc.: | Oil |
| Source: | The rhizomes of Curcuma zedoaria |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
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| Description | Furanodiene is a natural terpenoid isolated from Rhizoma Curcumae. Furanodiene plays anti-cancer effects through anti-angiogenesis and inducing ROS production, DNA strand breaks and apoptosis. Furanodiene suppresseed efflux transporter Pgp (P-glycoprotein) function and reduced Pgp protein level[1]. |
| In Vitro | Furanodiene (1.4, 4.1, 12.2 uM; 48 hours) is effective in treating human JF 305 pancreatic cancer cells and MCF-7 breast cancer cells xenotranplanted into the zebrafish[1]. Furanodiene has no effect on Pgp related gene (MDR1) expression[1]. |
| Density | 0.945±0.06 g/cm3 |
| Boiling Point | 309.6±11.0 °C at 760 mmHg |
| Exact Mass | 216.15100 |
| PSA | 13.14000 |
| LogP | 4.35940 |