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Delta3,2-Hydroxylbakuchiol
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Product Name Delta3,2-Hydroxylbakuchiol
Price: Inquiry
Catalog No.: CN03815
CAS No.: 178765-49-6
Molecular Formula: C18H24O2
Molecular Weight: 272.4 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Oil
Source: The herbs of Psoralea corylifolia Linn.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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Description Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol), an analog of Bakuchiol (HY-N0235) isolated from Psoralea corylifolia (L.), is a potent monoamine transporter inhibitor. 13-Hydroxyisobakuchiol is more selective for the dopamine transporter (DAT) (IC50=0.58 μM) and norepinephrine transporter (NET) (IC50=0.69 μM) than for the serotonin transporter (SERT) (IC50=312.02 μM). 13-Hydroxyisobakuchiol has the potential for the research of disorders such as Parkinson's disease, depression, and cocaine addiction[1].
Target IC50: 0.58 μM (dopamine transporter) IC50: 0.69 μM (norepinephrine transporter)[1]
Density1.0±0.1 g/cm3
Boiling Point429.3±45.0 °C at 760 mmHg
Flash Point195.8±23.3 °C
Exact Mass272.177643
LogP3.85
Vapour Pressure0.0±1.1 mmHg at 25°C