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Product Name | Delta3,2-Hydroxylbakuchiol |
Price: | Inquiry |
Catalog No.: | CN03815 |
CAS No.: | 178765-49-6 |
Molecular Formula: | C18H24O2 |
Molecular Weight: | 272.4 g/mol |
Purity: | >=98% |
Type of Compound: | Phenols |
Physical Desc.: | Oil |
Source: | The herbs of Psoralea corylifolia Linn. |
Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
SMILES: |
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Description | Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol), an analog of Bakuchiol (HY-N0235) isolated from Psoralea corylifolia (L.), is a potent monoamine transporter inhibitor. 13-Hydroxyisobakuchiol is more selective for the dopamine transporter (DAT) (IC50=0.58 μM) and norepinephrine transporter (NET) (IC50=0.69 μM) than for the serotonin transporter (SERT) (IC50=312.02 μM). 13-Hydroxyisobakuchiol has the potential for the research of disorders such as Parkinson's disease, depression, and cocaine addiction[1]. |
Target | IC50: 0.58 μM (dopamine transporter) IC50: 0.69 μM (norepinephrine transporter)[1] |
Density | 1.0±0.1 g/cm3 |
Boiling Point | 429.3±45.0 °C at 760 mmHg |
Flash Point | 195.8±23.3 °C |
Exact Mass | 272.177643 |
LogP | 3.85 |
Vapour Pressure | 0.0±1.1 mmHg at 25°C |