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Methyl trans-cinnamate
| Product Name | Methyl trans-cinnamate |
| Price: | Inquiry |
| Catalog No.: | CN06783 |
| CAS No.: | 1754-62-7 |
| Molecular Formula: | C10H10O2 |
| Molecular Weight: | 162.1 g/mol |
| Purity: | >=98% |
| Type of Compound: | Phenylpropanoids |
| Physical Desc.: | Powder |
| Source: | The essential oils of Zanthoxylum alatum. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COC(=O)/C=C/c1ccccc1 |
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| Description | Methyl (E)-cinnamate (EMC), a phytochemical constituent isolated from Alpinia katsumadai Hayata, is a natural flavor compound with anti-inflammatory properties. Methyl (E)-cinnamate is widely used in the food and commodity industry[1]. |
| In Vitro | Methyl (E)-cinnamate (0~30 μM; 24 hours; MC3T3-E1 cells) significantly increases the cleaved forms of poly (ADP-ribose) polymerase (PARP) and caspase-3, while it decreases the expression levels of Survivin and Bcl-2, and significantly increases TUNEL-positive and DAPI-stained cells[1]. Methyl (E)-cinnamate (0~30 μM;7 days; MC3T3-E1 cells) suppresses the osteoblast differentiation[1]. Methyl (E)-cinnamate (1~100 μM; 24 and 48 hours; MC3T3-E1 cells) decreases cell survival and induces morphological changes. EMC decreases MAPKs signaling and cell migration[1]. Western Blot Analysis[1] Cell Line: MC3T3-E1 cells Concentration: 0~30 μM Incubation Time: 24 hours Result: Significantly increased the cleaved forms of poly (ADP-ribose) polymerase (PARP) and caspase-3, while it decreased the expression levels of Survivin and Bcl-2. Apoptosis Analysis[1] Cell Line: MC3T3-E1 cells Concentration: 0~30 μM Incubation Time: 24 hours Result: Significantly increased TUNEL-positive and DAPI-stained cells. Cell Differentiation Assay[1] Cell Line: MC3T3-E1 cells Concentration: 0~30 μM Incubation Time: 7 days Result: Suppressed the osteoblast differentiation. |
| Density | 1.078 g/cm3 |
| Boiling Point | 261.9ºC at 760 mmHg |
| Flash Point | 141.3ºC |
| Exact Mass | 162.06800 |
| PSA | 26.30000 |
| LogP | 1.87280 |
| Vapour Pressure | 0.0112mmHg at 25°C |
| Storage condition | 2-8°C |