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Product Name Nitidanin
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Catalog No.: CN07002
CAS No.: 171674-89-8
Molecular Formula: C21H24O8
Molecular Weight: 404.4 g/mol
Purity: >=98%
Type of Compound: Phenylpropanoids
Physical Desc.: Powder
Source: The herbs of Zanthoxylum simulans Hance
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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Description Nitidanin ((±)-Nitidanin) is an antimalarial and antiviral compound that can be isolated from the wood of Xanthoxylum nitidun D. C. Nitidanin is shows IC50 values of 21.2 and 18.4 μM for D6 and W2 clones of Plasmodium falciparum, respectively. Nitidanin can be used for the research of malaria and virus infection[1][2].
In Vitro Nitidanin 对恶性疟原虫的 D6 和 W2 克隆品有抑制作用,IC50 值分别为 21.2 和 18.4 μM[1]。 Nitidanin 对人口腔表皮样癌细胞 (KB) 显示出非细胞毒性作用,EC50值 >99 μM[1]。 Nitidanin 对人肝癌 Huh7.5.1 细胞具有较低的细胞毒性作用,CC50 值为 464.4 μM[2]。 Nitidanin (0-250 μM;5 小时) 表现出抗 HCV 活性,IC50 值为 200 μM[2]。
Density1.3±0.1 g/cm3
Boiling Point622.2±55.0 °C at 760 mmHg
Flash Point330.1±31.5 °C
Exact Mass404.147125
PSA106.84000
LogP0.56
Vapour Pressure0.0±1.9 mmHg at 25°C