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Cyasterone
| Product Name | Cyasterone |
| Price: | $62 / 20mg |
| Catalog No.: | CN02509 |
| CAS No.: | 17086-76-9 |
| Molecular Formula: | C29H44O8 |
| Molecular Weight: | 520.65 g/mol |
| Purity: | >=98% |
| Type of Compound: | Steroids |
| Physical Desc.: | Powder |
| Source: | The roots of Cyathula officinalis Kuan. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | O[C@H]1C[C@@]2(C)[C@@H](C[C@H]1O)C(=O)C=C1[C@@H]2CC[C@]2(C1(O)CC[C@@H]2[C@]([C@@H](C[C@@H]1[C@@H](O)COC(=O)[C@H]1C)O)(O)C)C |
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| Description | Cyasterone, a natural EGFR inhibitor, mainly isolated from Ajuga decumbens Thunb (Labiatae).Cyasterone manifests anti-proliferation effect by induced apoptosis and cell cycle arrests. Cyasterone may serves as a clinical therapeutic anti-tumor agent against human tumors[1]. |
| In Vitro | Cyasterone (0-100μM; 24hours) inhibits cell growth in a concentration-and time-dependent manner, IC50 values are 38.50 mg/mL, 32.96 mg/mL in A549 and MGC823 cells ,respectively[1]. Cell Viability Assay[1] Cell Line: A549, HCT116, MGC823 cells Concentration: 0-100 μM Incubation Time: 24 hours Result: Inhibited the growth of 3 human cancer lines A549, HCT116, MGC823 cells. |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 742.8±60.0 °C at 760 mmHg |
| Flash Point | 242.0±26.4 °C |
| Exact Mass | 520.303589 |
| PSA | 144.52000 |
| LogP | -0.25 |
| Vapour Pressure | 0.0±5.6 mmHg at 25°C |