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Laudanosine
| Product Name | Laudanosine |
| Price: | Inquiry |
| Catalog No.: | CN00611 |
| CAS No.: | 1699-51-0 |
| Molecular Formula: | C21H27NO4 |
| Molecular Weight: | 357.5 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | The main metabolite of atracurium. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COc1cc(ccc1OC)CC1N(C)CCc2c1cc(OC)c(c2)OC |
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| Description | DL-Laudanosine, an Atracurium and Cisatracurium metabolite, crosses the blood–brain barrier and may cause excitement and seizure activity[1]. |
| In Vivo | DL-Laudanosine (Laudanosine) appears to be unique in its ability to produce cerebral stimulation in lightly anaesthetized animals and it is reported to cause arousal from anaesthesia in subconvulsive doses[1]. Animal Model: Male CFLP mice weighing 18-25 g, and male Wistar rats weighing 120-150 g [2]. Dosage: 10-20 mg/kg. Administration: IV. Result: Caused convulsions and hind limb extensions. |
| Exact Mass | 357.19400 |
| PSA | 40.16000 |
| LogP | 3.43060 |