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Coniine hydrochloride
| Product Name | Coniine hydrochloride |
| Price: | Inquiry |
| Catalog No.: | CN00612 |
| CAS No.: | 15991-59-0 |
| Molecular Formula: | C8H18ClN |
| Molecular Weight: | 163.7 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | The herbs of Oenanthe javanica |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | CCCC1CCCCN1.Cl |
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| Description | (±)-Coniine hydrochloride (2-Propylpiperidine hydrochloride) is a potent nAChR agonist with an EC50 value of 0.3 mM. (±)-Coniine hydrochloride shows acute toxicity with an LD50 value of 7.7 mg/kg[1]. |
| Target | EC50: 0.3 mM (nAChR)[1] |
| In Vivo | (±)-Coniine hydrochloride (compound 1) (0.05 mg-0.2 mg; i.v.) 具有急性毒性，LD50 值为 7.7 mg/kg[1]。 Animal Model: 15-20 g, Swiss-Webster male mice[1] Dosage: 0.05 mg-0.2 mg Administration: I.v. Result: Clinical signs was almost immediate after injection, beginning with piloerection, tailflicking, and rapidly progressing to intention tremors, clonic convulsions, muscular weakness, lateral recumbency, and death; shows acute toxicity with an LD50 value of 7.7 mg/kg. |
| Boiling Point | 166.2ºC at 760 mmHg |
| Flash Point | 48.4ºC |
| Exact Mass | 163.11300 |
| PSA | 12.03000 |
| LogP | 3.05940 |
| Vapour Pressure | 1.8mmHg at 25°C |