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4'-Hydroxy-2,4-dimethoxychalcone
| Product Name | 4'-Hydroxy-2,4-dimethoxychalcone |
| Price: | $351 / 5mg |
| Catalog No.: | CN05611 |
| CAS No.: | 151135-64-7 |
| Molecular Formula: | C17H16O4 |
| Molecular Weight: | 284.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Chalcones |
| Physical Desc.: | Powder |
| Source: | The herbs of Bauhinia glauca |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COc1cc(OC)ccc1/C=C/C(=O)c1ccc(cc1)O |
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| Description | 4'-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4'-Hydroxy-2,4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity[1][2]. |
| In Vitro | 4'-Hydroxy-2,4-dimethoxychalcone (compound 2) is against P. falciparum D6 (IC50=4.2 μM) and W2 (IC50=4.8 μM)[1]. |
| In Vivo | 4'-Hydroxy-2,4-dimethoxychalcone (compound 2; oral; 160 mg/kg) has a T1/2 of 1.94 hours, a Cmax of 158 ng/mL and an AUC of 384 ng•h/mL in four- to five-week-old ICR mice[1]. |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 500.1±50.0 °C at 760 mmHg |
| Flash Point | 185.8±23.6 °C |
| Exact Mass | 284.104858 |
| LogP | 3.48 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Storage condition | 2-8℃ |