Description |
Strictosidinic acid, an orally active glycoside indole monoterpene alkaloid isolated from Psychotria myriantha leaves, inhibits precursor enzymes of 5-HT biosynthesis and reduces the 5-HT levels. Strictosidinic acid has peripheral analgesic and antipyretic activities in mice[1][2].
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Target |
5-HT Receptor
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In Vivo |
Strictosidinic acid (20 μg/μl; intra-hippocampal injection) causes a significance of 83.5% reduction in 5-HT levels. Strictosidinic acid (10 mg/kg; i.p.) causes a 63.4% reduction in 5-HT levels and a 67.4% reduction in DOPAC values in male Wistar rats, weighing 200-250 g[1].
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Density | 1.5±0.1 g/cm3 |
Boiling Point | 792.8±60.0 °C at 760 mmHg |
Flash Point | 433.3±32.9 °C |
Exact Mass | 516.210754 |
LogP | -0.23 |
Vapour Pressure | 0.0±2.9 mmHg at 25°C |
Storage condition | 2-8℃ |