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3,4-Dihydroxybenzaldehyde
| Product Name | 3,4-Dihydroxybenzaldehyde |
| Price: | $15 / 20mg |
| Catalog No.: | CN04121 |
| CAS No.: | 139-85-5 |
| Molecular Formula: | C7H6O3 |
| Molecular Weight: | 138.1 g/mol |
| Purity: | >=98% |
| Type of Compound: | Phenols |
| Physical Desc.: | Powder |
| Source: | The heartwoods of Cassia garrettiana. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | O=Cc1ccc(c(c1)O)O |
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| Description | Protocatechualdehyde (Catechaldehyde), a natural polyphenol compound isolated from the roots of radix Salviae Miltiorrhizae, is associated with a wide variety of biological activities and has been widely used in medicine as an antioxidant, anti-aging, an antibacterial and anti-inflammatory agent[1]. |
| In Vitro | Protocatechualdehyde (PCA) (50, 100 μM, 24/48 hours ) treated MCF-7 cells significantly decrease cell growth by 11% and 20% in 24 hours and by 22% and 27% in 48 hours, respectively[2]. Protocatechualdehyde (50, 100 μM, 24 hours) treated MCF-7 cells are increased by 1.9-fold and 2.6-fold in the concentrations of 50 μM and 100 μM, respectively. PCA suppresses proliferation of estrogen receptor (ER)-positive (MCF-7) breast cancer cells, but not ER-negative (MDA-MB-231) breast cancer cells[2]. Protocatechualdehyde (0, 100, 200 μM, 48 hours in HCT116 and SW480 cells) affects the enzyme activity of HDAC and observed that PCA treatment resulted in inhibition of HDAC activity in dose-dependent manner[3]. Cell Proliferation Assay[2] Cell Line: Human breast cancer cell (MCF-7 and MDA-MB-231) Concentration: 0, 5, 10, 25, 50, and 100 μM Incubation Time: 24, 48 hours Result: inhibited MCF-7 cells cell growth. Apoptosis Analysis[2] Cell Line: Human breast cancer cell (MCF-7 and MDA-MB-231) Concentration: 0, 5, 10, 25, 50, and 100 μM Incubation Time: 24, 48 hours Result: increased apoptosis in MCF-7 cells. |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 295.4±20.0 °C at 760 mmHg |
| Flash Point | 146.7±18.3 °C |
| Exact Mass | 138.031693 |
| PSA | 57.53000 |
| LogP | 1.14 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Storage condition | 2-8°C |