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Diphlorethohydroxycarmalol
| Product Name | Diphlorethohydroxycarmalol |
| Price: | Inquiry |
| Catalog No.: | CN05712 |
| CAS No.: | 138529-04-1 |
| Molecular Formula: | C24H16O13 |
| Molecular Weight: | 512.4 g/mol |
| Purity: | >=98% |
| Type of Compound: | Xanthones |
| Physical Desc.: | Powder |
| Source: | |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | Diphlorethohydroxycarmalol, a kind of phlorotannin, is an orally active α-glucosidase and α-amylase inhibitor with IC50s of 0.16 mM and 0.53 mM, respectively. Diphlorethohydroxycarmalol has anti-diabetic activities[1]. |
| Target | IC50: 0.16 mM (α-glucosidase) and 0.53 mM (α-amylase) [1] |
| In Vivo | The increase of postprandial blood glucose levels are significantly suppressed in the Diphlorethohydroxycarmalol-administered group than those in the streptozotocin-induced diabetic or normal mice. Moreover, the area under curve (AUC) is significantly reduced via Diphlorethohydroxycarmalol (100 mg/kg; p.o.) administration (2022 versus 2210 mmol x min/lL) in the diabetic mice as well as it delays absorption of dietary carbohydrates[1]. |
| Exact Mass | 512.05900 |
| PSA | 218.99000 |
| LogP | 4.51960 |