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Ponasterone A
| Product Name | Ponasterone A |
| Price: | Inquiry |
| Catalog No.: | CN02594 |
| CAS No.: | 13408-56-5 |
| Molecular Formula: | C27H44O6 |
| Molecular Weight: | 464.6 g/mol |
| Purity: | >=98% |
| Type of Compound: | Steroids |
| Physical Desc.: | Powder |
| Source: | The barks of Podocarpus macrophyllus |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: |
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| Description | Ponasterone A (25-Deoxyecdysterone), an ecdysteroid, has strong affinity for the ecdysone receptor. Ponasterone A is a potent regulator of gene expression in cells and transgenic animals, enabling reporter genes to be turned on and off rapidly[1][2]. |
| Target | ecdysone receptor[2] |
| In Vitro | Ponasterone A (1 nM-100 μM) shows significant gene induction activity in CV-1 cells[2]. |
| In Vivo | Ponasterone A (3-10 mg; i.p.) produces robust inductions of gene expression in transactivator and reporter mice[2]. |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 640.5±55.0 °C at 760 mmHg |
| Flash Point | 355.2±28.0 °C |
| Exact Mass | 464.313782 |
| PSA | 118.22000 |
| LogP | 1.55 |
| Vapour Pressure | 0.0±4.3 mmHg at 25°C |
| Storage condition | −20°C |