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Aristololactam I
| Product Name | Aristololactam I |
| Price: | $176 / 10mg |
| Catalog No.: | CN01341 |
| CAS No.: | 13395-02-3 |
| Molecular Formula: | C17H11NO4 |
| Molecular Weight: | 293.27 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Cryst. |
| Source: | The herbs of Aristolochia debilis Sieb. et Zucc |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COc1cccc2c1cc1[nH]c(=O)c3c1c2c1OCOc1c3 |
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| Description | Aristololactam I (AL-I), is the main metabolite of aristolochic acid I (AA-I), participates in the processes that lead to renal damage.Aristololactam I (AL-I) directly injures renal proximal tubule cells, the cytotoxic potency of AL-I is higher than that of AA-I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase-3-dependent pathway[1]. |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 463.9±34.0 °C at 760 mmHg |
| Flash Point | 234.4±25.7 °C |
| Exact Mass | 293.068817 |
| PSA | 60.55000 |
| LogP | 2.97 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |