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Tryptanthrine
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Product Name Tryptanthrine
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Catalog No.: CN00693
CAS No.: 13220-57-0
Molecular Formula: C15H8N2O2
Molecular Weight: 248.2 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The leaves of Strobilanthes cusia
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
SMILES: O=C1c2nc3ccccc3c(=O)n2c2c1cccc2
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Description Tryptanthrin is a potent and orally active cellular Leukotriene (LT) biosynthesis inhibitor. Tryptanthrin inhibits LT formation in human whole blood (IC50 = 10 µM) and reduces LTB4 levels in the rat pleurisy model[1].
Target IC50: 10 µM (LT formation in human whole blood)[1]
Density1.45g/cm3
Boiling Point469.3ºC at 760 mmHg
Flash Point237.7ºC
Exact Mass248.05900
PSA51.96000
LogP1.93010
Vapour Pressure5.55E-09mmHg at 25°C