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Cornuside
| Product Name | Cornuside |
| Price: | Inquiry |
| Catalog No.: | CN03158 |
| CAS No.: | 131189-57-6 |
| Molecular Formula: | C24H30O14 |
| Molecular Weight: | 542.49 g/mol |
| Purity: | >=98% |
| Type of Compound: | Iridoids |
| Physical Desc.: | Powder |
| Source: | The fruits of Cornus officinalis Sieb. et Zucc. |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | C=C[C@H]1[C@@H](OC=C([C@H]1CCOC(=O)c1cc(O)c(c(c1)O)O)C(=O)OC)O[C@@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O |
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| Description | Cornuside is a secoiridoid glucoside isolated from the fruit of Cornus officinalis Sieb. et Zucc., which is a traditional oriental medicine for treating inflammatory diseases and invigorating blood circulation. Cornuside inhibits mast cell-mediated allergic response by down-regulating MAPK and NF-κB signaling pathways. Cornuside has anti-allergic effects in vivo and in vitro which suggests a therapeutic application of this agent in inflammatory allergic diseases[1]. |
| Target | p38 MAP kinase NF-κB |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 817.6±65.0 °C at 760 mmHg |
| Flash Point | 274.5±27.8 °C |
| Exact Mass | 542.163574 |
| PSA | 221.90000 |
| LogP | -0.31 |
| Vapour Pressure | 0.0±3.1 mmHg at 25°C |