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alpha-Yohimbine
| Product Name | alpha-Yohimbine |
| Price: | Inquiry |
| Catalog No.: | CN02220 |
| CAS No.: | 131-03-3 |
| Molecular Formula: | C21H26N2O3 |
| Molecular Weight: | 354.5 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | The barks of Pausinystalia yohimbe |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | Rauwolscine is a selective α2-adrenoceptor antagonist that inhibits tumor growth and induces apoptosis[1]. |
| In Vivo | Rauwolscine (0.5 mg/kg, daily) 通过增强细胞凋亡和减少细胞增殖来减少 Balb/c 雌性小鼠的肿瘤生长[1]。 Rauwolscine (i.v., 2.24 mg/kg) 能明显释放大鼠的舔食冲突反应，类似于α受体激动剂 clonidine (0.022 mg/kg) 和benzodiazepine diazepam (0.5 mg/kg)[2]。 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 543.0±50.0 °C at 760 mmHg |
| Flash Point | 282.2±30.1 °C |
| Exact Mass | 354.194336 |
| PSA | 65.56000 |
| LogP | 2.20 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |