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Siamenoside I
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Product Name Siamenoside I
Price: $263 / 10mg
Catalog No.: CN07750
CAS No.: 126105-12-2
Molecular Formula: C54H92O24
Molecular Weight: 1125.29 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The leaves of Momordica grosvenori Swingle
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
SMILES: OC[C@H]1O[C@@H](O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O)CO[C@@H]2O[C@H](CO)[C@H]([C@@H]([C@H]2O)O)O)O[C@@H](C(O)(C)C)CC[C@H]([C@H]2CC[C@@]3([C@]2(C)C[C@@H](O)[C@@]2([C@H]3CC=C3[C@H]2CC[C@@H](C3(C)C)O[C@@H]2O[C@H](CO)[C@H]([C@@H]([C@H]2O)O)O)C)C)C)[C@@H]([C@H]([C@@H]1O)O)O
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Description Siamenoside I is one of the mogrosides that has several kinds of bioactivities.
In Vivo In rat, the metabolic reactions of siamenoside I include deglycosylation, hydroxylation, dehydrogenation, deoxygenation, isomerization, and glycosylation. Siamenoside I and its metabolites are mainly distributed to the intestines, stomach, kidneys, and brain[1].
Animal Admin The animal experiment lasts six days. The whole urine and feces of days 1-2 are collected as blank urine and feces samples, respectively. On days 3-5, the rats of test group are orally administrated with siamenoside I [50 mg/kg body weight, in normal saline (NS) solution] at 9:00, and all 72-h urine and feces are collected as drug-containing urine and feces samples, respectively. The rats of blank group are orally administrated with the same volume of NS. On day 6 at 9:00, the test and the blank group are treated with siamenoside I and NS again, respectively. After 1 h, blood sample is collected into a vacuum tube with sodium citrate as anticoagulant from rat heart under anesthesia. Then, the organs (heart, liver, spleen, lung, kidneys, stomach, small intestine, brain) and skeletal muscles of rats are collected and washed with NS, separately. All samples are kept at −80°C before further pretreatment.
Density1.5±0.1 g/cm3
Boiling Point1179.3±65.0 °C at 760 mmHg
Flash Point667.0±34.3 °C
Exact Mass1124.597900
PSA397.52000
LogP-0.77
Vapour Pressure0.0±0.6 mmHg at 25°C
Storage condition2-8℃