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Lavendustin A
| Product Name | Lavendustin A |
| Price: | Inquiry |
| Catalog No.: | CN01865 |
| CAS No.: | 125697-92-9 |
| Molecular Formula: | C21H19NO6 |
| Molecular Weight: | 381.38 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | From Streptomyces griseolavendus |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | Lavendustin A (RG-14355), isolated from Streptomyces Griseolavendus, is a potent, specific and ATP-competitive inhibitor of tyrosine kinase, with an IC50 of 11 ng/mL for EGFR-associated tyrosine kinase[1]. It suppresses VEGF-induced angiogenesis and blocks the induction of LTPGABA-A[2][3]. |
| Target | IC50: 11 ng/mL (EGFR-associated tyrosine kinase)[1]. |
| Boiling Point | 741.7ºC at 760 mmHg |
| Flash Point | 402.4ºC |
| Exact Mass | 381.12100 |
| PSA | 121.46000 |
| LogP | 3.41400 |
| Vapour Pressure | 4.23E-23mmHg at 25°C |
| Storage condition | −20°C |