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Moracin O
| Product Name | Moracin O |
| Price: | $351 / 10mg |
| Catalog No.: | CN03771 |
| CAS No.: | 123702-97-6 |
| Molecular Formula: | C19H18O5 |
| Molecular Weight: | 326.4 g/mol |
| Purity: | >=98% |
| Type of Compound: | Phenols |
| Physical Desc.: | Powder |
| Source: | The root barks of Morus alba L. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | Moracin O is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin O reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin O has neuroprotective and anti-inflammatory effects[1][2][3]. |
| In Vitro | Moracin O enhances cell viability in dose-dependent manner against oxygen-glucose deprivation (OGD)-induced cell death in neuroblastoma SH-SY5Y cells with an EC50 value of 12.6 μM. Moracin O reduces ROS production in OGD-induced cell death (IC50 value of 0.3 μM). Moracin O protects neuronal cell death against the oxidative stress induced by OGD[1]. |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 557.0±38.0 °C at 760 mmHg |
| Flash Point | 290.6±26.8 °C |
| Exact Mass | 326.115417 |
| PSA | 83.06000 |
| LogP | 2.86 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Storage condition | 2-8℃ |