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Phyltetralin
| Product Name | Phyltetralin |
| Price: | Inquiry |
| Catalog No.: | CN02881 |
| CAS No.: | 123048-17-9 |
| Molecular Formula: | C24H32O6 |
| Molecular Weight: | 416.5 g/mol |
| Purity: | >=98% |
| Type of Compound: | Lignans |
| Physical Desc.: | Powder |
| Source: | The herbs of Phyllanthus niruri Linn. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | Phyltetralin (Compound 10) is a natural product than can be isolated from the hexane-ethyl acetate extract of Phyllanthus amarus leaves. Phyltetralin possesses immunosuppressive effects on different lineages of innate immune system[1][2]. |
| In Vitro | Phyltetralin shows inhibition on Polymorphonuclear neutrophil (PMN) chemotaxis with an IC50 of 4.01 µM[2]. Phyltetralin shows strong inhibition against reactive oxygen species (ROS) production from PMA-stimulated neutrophil with an IC50 of 0.73 µM[2]. Phyltetralin shows weak inhibition on CD18 expression and moderate inhibition on engulfment activity[2]. |
| Exact Mass | 416.22000 |
| PSA | 55.38000 |
| LogP | 3.93420 |