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Huperzine A
| Product Name | Huperzine A |
| Price: | Inquiry |
| Catalog No.: | CN02123 |
| CAS No.: | 120786-18-7 |
| Molecular Formula: | C15H18N2O |
| Molecular Weight: | 242.32 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | The herbs of Lycopodium serratum |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | C/C=C/1C2C=C(CC1(N)c1c(C2)[nH]c(=O)cc1)C |
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| Description | Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD). IC50 value:Target: AChEHuperzine A exhibited protective effects against d-gal-induced hepatotoxicity and inflamm-aging by inhibiting AChE activity and via the activation of the cholinergic anti-inflammatory pathway. The huperzine A mechanism might be involved in the inhibition of DAMPs-mediated NF-κB nuclear localization and activation. Huperzine A is a potential therapeutic agent for Alzheimer's disease. |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 505.0±50.0 °C at 760 mmHg |
| Flash Point | 259.2±30.1 °C |
| Exact Mass | 242.141907 |
| PSA | 58.88000 |
| LogP | 0.71 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Storage condition | 2-8°C |