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Product Name | Glychionide A |
Price: | $556 / 5mg |
Catalog No.: | CN05076 |
CAS No.: | 119152-50-0 |
Molecular Formula: | C21H18O11 |
Molecular Weight: | 446.4 g/mol |
Purity: | >=98% |
Type of Compound: | Flavonoids |
Physical Desc.: | Yellow powder |
Source: | The roots of Glychirriza glabra L. |
Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
SMILES: |
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Description | Glychionide A is a flavonoside that can be found in the roots of Glychirriza glabra. Glychionide A promotes apoptosis and autophagy of PANC-1 pancreatic cancer cells. Glychionide A can be used for the research of cancer[1][2]. |
In Vitro | Glychionide A (3.12-100 μM) significantly inhibits the proliferation of the PANC-1 pancreatic cancer cells, with an IC50 of 14 μM[1]. Glychionide A (7-28 μM) induces both autophagy and apoptosis in pancreatic cancer cells[1]. Glychionide A (7-28 μM) causes G2/M arrest of PANC-1 pancreatic cancer cells[1]. Glychionide A (7-28 μM) causes generation of ROS in PANC-1 cells[1]. |
Density | 1.7±0.1 g/cm3 |
Boiling Point | 839.4±65.0 °C at 760 mmHg |
Flash Point | 298.2±27.8 °C |
Exact Mass | 446.084900 |
LogP | -1.03 |
Vapour Pressure | 0.0±3.3 mmHg at 25°C |