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Aurora A Inhibitor I (TC-S 7010)
| Product Name | Aurora A Inhibitor I (TC-S 7010) |
| Price: | Inquiry |
| Catalog No.: | CN00300 |
| CAS No.: | 1158838-45-9 |
| Molecular Formula: | C31H31ClFN7O2 |
| Molecular Weight: | 588.07 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | CCN1CCN(CC1)C(=O)Cc1ccc(cc1)Nc1ncc(c(n1)Nc1ccc(cc1)C(=O)Nc1ccccc1Cl)F |
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| Description | Aurora A inhibitor I is a potent and highly selective Aurora A inhibitor with with an IC50 of 3.4 nM. |
| Target | Aurora A:3.4 nM (IC50) Aurora B:3.4 μM (IC50) |
| In Vitro | Aurora A inhibitor I is exceptionally selective Aurora A inhibitors. Aurora A inhibitor I is an useful tool compounds for investigating the cellular role of Aurora A kinases without the complication of also inhibiting Aurora B[1]. |
| Density | 1.4±0.1 g/cm3 |
| Exact Mass | 587.221191 |
| PSA | 102.49000 |
| LogP | 4.39 |
| Storage condition | 2-8°C |