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Quetiapine fumarate
| Product Name | Quetiapine fumarate |
| Price: | Inquiry |
| Catalog No.: | CN02054 |
| CAS No.: | 111974-72-2 |
| Molecular Formula: | (C2H21N25O3S).C2H4O44 |
| Molecular Weight: | 883.09 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | The herbs of Ampelopsis japonica (Thunb.) Makino |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | OC(=O)C=CC(=O)O.OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2c1cccc2.OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2c1cccc2 |
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| Description | Quetiapine fumarate is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression.IC50 value: Target: 5-HT ReceptorQuetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The antipsychotic effect of quetiapine is thought by some to be mediated through antagonist activity at dopamine and serotonin receptors. Specifically the D1 and D2 dopamine, the alpha 1 adrenoreceptor and alpha 2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also has an antagonistic effect on the histamine H1 receptor. |
| Boiling Point | 556.5ºC at 760 mmHg |
| Flash Point | 290.4ºC |
| PSA | 221.80000 |
| LogP | 4.04660 |
| Vapour Pressure | 3.22E-13mmHg at 25°C |
| Storage condition | -20°C Freezer |