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BIX02189
| Product Name | BIX02189 |
| Price: | Inquiry |
| Catalog No.: | CN00483 |
| CAS No.: | 1094614-85-3 |
| Molecular Formula: | C27H28N4O2 |
| Molecular Weight: | 440.54 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | CN(Cc1cccc(c1)N/C(=C/1C(=O)Nc2c1ccc(c2)C(=O)N(C)C)/c1ccccc1)C |
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| Description | (E/Z)-BIX02189 is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
| In Vitro | BIX 02189 是一种选择性的 MEK5 抑制剂，IC50 为 1.5 nM，也抑制 ERK5 的催化活性，IC50 为 810 nM，而不抑制其密切相关的激酶 MEK1、MEK2、ERK2 和 JNK2。 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 653.4±55.0 °C at 760 mmHg |
| Flash Point | 349.0±31.5 °C |
| Exact Mass | 440.221222 |
| PSA | 64.68000 |
| LogP | 2.05 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Storage condition | -20℃ |