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Taccalonolide B
| Product Name | Taccalonolide B |
| Price: | $293 / 10mg |
| Catalog No.: | CN02440 |
| CAS No.: | 108885-69-4 |
| Molecular Formula: | C34H44O13 |
| Molecular Weight: | 660.71 g/mol |
| Purity: | >=98% |
| Type of Compound: | Steroids |
| Physical Desc.: | Powder |
| Source: | The rhizomes of Schizocapsa plantaginea Hance. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | CC(=O)O[C@H]1[C@@H](OC(=O)C)[C@H]2[C@H]([C@H]3[C@@]1(C)[C@H]1[C@H](C)C=C4[C@]([C@@H]1[C@@H]3O)(C)[C@](C)(O)C(=O)O4)[C@@H](O)C(=O)[C@@H]1[C@]2(C)[C@@H](OC(=O)C)[C@H]2O[C@H]2C1 |
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| Description | Taccalonolide B is microtubule stabilizer isolated from Tacca plantaginea, with antitumor activity. Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibits growth of SK-OV-3 cells with an IC50 of 208 nM[1][2]. |
| Target | microtubule[2] |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 775.9±60.0 °C at 760 mmHg |
| Flash Point | 242.4±26.4 °C |
| Exact Mass | 660.278198 |
| PSA | 195.49000 |
| LogP | 1.88 |
| Vapour Pressure | 0.0±6.0 mmHg at 25°C |