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Ganoderic acid R
| Product Name | Ganoderic acid R |
| Price: | Inquiry |
| Catalog No.: | CN07240 |
| CAS No.: | 103963-39-9 |
| Molecular Formula: | C34H50O6 |
| Molecular Weight: | 554.76 g/mol |
| Purity: | >=98% |
| Type of Compound: | Triterpenoids |
| Physical Desc.: | Powder |
| Source: | The fruit body of Ganoderma lucidum |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | Ganoderic acid R is a potent anticancer agent. Ganoderic acid R inhibits the growth by inducing apoptosis on tumor cell line. Ganoderic acid R possesses significant cytotoxicity on a multidrug resistance (MDR) tumor cell line (KB-A-1/Dox) and a sensitive tumor cell line (KB-A-1)[1]. |
| In Vitro | Ganoderic acid R (0-50 µg/mL, 48 h) 在浓度超过 20 µg/mL时通过诱导肿瘤细胞系凋亡来抑制生长[1]。 Apoptosis Analysis[1] Cell Line: KB-A-1/Dox cells Concentration: 0, 25, 50 μg/mL Incubation Time: 48 h Result: Induced the cellular apoptosis, the number of apoptotic cells was increased from 35% to 90% during 48 h. |
| Exact Mass | 554.36100 |
| PSA | 89.90000 |
| LogP | 7.43220 |