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Moracin P
| Product Name | Moracin P |
| Price: | $380 / 5mg |
| Catalog No.: | CN03889 |
| CAS No.: | 102841-46-3 |
| Molecular Formula: | C19H18O5 |
| Molecular Weight: | 326.4 g/mol |
| Purity: | >=98% |
| Type of Compound: | Phenols |
| Physical Desc.: | Powder |
| Source: | The root barks of Morus alba L. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | Moracin P is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin P reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin P has neuroprotective and anti-inflammatory effects[1][2][3]. |
| In Vitro | Moracin P enhances cell viability in dose-dependent manner against oxygen-glucose deprivation (OGD)-induced cell death in neuroblastoma SH-SY5Y cells with an EC50 value of 10.4 μM. Moracin P reduces ROS production in OGD-induced cell death (IC50 values of 1.9 μM). Consequently, reactive oxygen species (ROS) are overexpressed in OGD-induced cells and Moracin P reduces ROS induced by OGD in dosedependent manner[1]. |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 560.6±50.0 °C at 760 mmHg |
| Flash Point | 292.8±30.1 °C |
| Exact Mass | 326.115417 |
| PSA | 83.06000 |
| LogP | 3.19 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |