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(-)-Huperzine A
| Product Name | (-)-Huperzine A |
| Price: | $54 / 20mg |
| Catalog No.: | CN02124 |
| CAS No.: | 102518-79-6 |
| Molecular Formula: | C15H18N2O |
| Molecular Weight: | 242.32 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | The herbs of Lycopodium serratum |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | C/C=C/1[C@H]2C=C(C[C@]1(N)c1c(C2)[nH]c(=O)cc1)C |
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| Description | Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD). IC50 value:Target: AChEHuperzine A exhibited protective effects against d-gal-induced hepatotoxicity and inflamm-aging by inhibiting AChE activity and via the activation of the cholinergic anti-inflammatory pathway. The huperzine A mechanism might be involved in the inhibition of DAMPs-mediated NF-κB nuclear localization and activation. Huperzine A is a potential therapeutic agent for Alzheimer's disease. |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 479.5±25.0 °C at 760 mmHg |
| Flash Point | 243.8±23.2 °C |
| PSA | 58.88000 |
| LogP | -0.22 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Storage condition | −20°C |