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Piceatannol
| Product Name | Piceatannol |
| Price: | $31 / 20mg |
| Catalog No.: | CN04151 |
| CAS No.: | 10083-24-6 |
| Molecular Formula: | C14H12O4 |
| Molecular Weight: | 244.2 g/mol |
| Purity: | >=98% |
| Type of Compound: | Phenols |
| Physical Desc.: | Powder |
| Source: | The rhizomes of Polygonum cuspidatum Sieb. et Zucc. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | Oc1cc(/C=C/c2ccc(c(c2)O)O)cc(c1)O |
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| Description | Piceatannol is a selective inhibitor of protein tyrosine kinase Syk. It could inhibit ICa,L, Ito, IKr, Ca2+ transients and Na+-Ca2+ exchange except IK1. Shows multiple biological activities such as anti-inflammatory, antiproliferative and immunomodulatory effects.In vitro: The treatment of human myeloid cells with piceatannol suppressed TNF-induced DNA binding activity of NF-κB. The effect of piceatannol was not restricted to myeloid cells, as TNF-induced NF-κB activation was also suppressed in lymphocyte and epithelial cells. Piceatannol also inhibited NF-κB activated by H2O2, PMA, LPS, okadaic acid, and ceramide. [1] |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 507.3±38.0 °C at 760 mmHg |
| Flash Point | 252.2±21.4 °C |
| Exact Mass | 244.073563 |
| PSA | 80.92000 |
| LogP | 2.69 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Storage condition | 2-8°C |